DEVELOPMENT OF A HYPEROSMOTIC STRESS INDUCIBLE GENE EXPRESSION SYSTEM BY ENGINEERING THE MTRA/MTRB-DEPENDENT NCGL1418 PROMOTER IN CORYNEBACTERIUM GLUTAMICUM

Corynebacterium glutamicum is an important workhorse for industrial production of diversiform bioproducts.Precise regulation of gene expression is crucial for metabolic balance and enhancing production of target molecules.Auto-inducible promoters, which can be activated without expensive inducers, are ideal regulatory tools for industrial-scale app

Abstract Graphite in metasedimentary rocks of the Eoarchean Saglek-Hebron Gneiss Complex (copyright) is depleted in 13C and has been interpreted as one gildan antique orange of the oldest traces of life on Earth.The variation in crystallinity of this oldest graphitic carbon could possibly confirm the effect of metamorphism on original biomass, but

Abstract Periodontitis is a chronic inflammatory disease that leads to the destruction of both soft and hard periodontal tissues.Complete periodontal regeneration in clinics using the currently available treatment approaches is still a challenge.Mesenchymal stem cells (MSCs) have shown promising potential to regenerate periodontal tissue in various

The observability of a dynamical system is affected by the presence of external inputs, either known (such as control actions) or unknown (disturbances).Inputs of unknown magnitude are especially detrimental for observability, and they also complicate its analysis.Hence, the availability of computational tools capable of analysing the observability

In this case study we investigate the source region of whistler-mode chorus synovex one grass located close to the geomagnetic equator at a radial distance of 4.4 Earth radii.We use measurements from the four Cluster spacecraft at separations of less than a few hundreds of km, recorded during the geomagnetic storm of 18 April 2002.The waveforms of